ifn-cd8

Purified CD8+ T cells produced IFN-γ in vitro when stimulated by type I IFN or IL-12 in combination with IL-18. Activated macrophages and DCs are major ...

由 SA Ghanekar 著作 · 2001 · 被引用 133 次 — IFN-γ expression is a functional surrogate marker for identifying CTL. We observed a broad range of CD8+ T-cell responses to the dominant epitope of CMV among ...

由 N Buang 著作 · 2021 · 被引用 58 次 — Our data suggest that type I IFN exposure contributes to SLE pathogenesis by promoting CD8+ T cell death via metabolic rewiring. Publication ...

We propose that, early in the immune response, IFNγ produced by a CD8+ T cell can act directly upon the cell itself, or upon neighboring CD8+ T cells, enhancing ...

由 M Abd Hamid 著作 · 2020 · 被引用 9 次 — Interferon gamma (IFNγ) supports effector responses of CD8+ cytotoxic T lymphocytes (CTLs) and is a surrogate marker for detection of ...

由 LFK Uhl 著作 · 2023 — IFN-γ controls CD8+ T-cell differentiation, expansion and the immunodominance of the T-cell response. Because IFN-γ regulates T-cell responses ...

由 P Bhat 著作 · 2017 · 被引用 411 次 — The ability of CD8 T cells to produce IFNγ enhanced their ability to migrate to the site of antigen-presenting skin cells. By in vivo imaging, ...

由 GA Kolumam 著作 · 2005 · 被引用 1152 次 — Direct action of IFN-I on antigen-specific CD8 T cells is critical for their expansion after viral infection. To directly address the role of IFN-IR in ...

由 BP Nicolet 著作 · 2020 · 被引用 74 次 — The surface molecules CD29 and CD38 helped identify the cytotoxic IFN-γ–producing T cells, and the noncytotoxic IL-2–producing CD8+ T cells, ...